“Mixing” Johnson and Johnson vaccines with Moderna increases antibodies 76 times


According to a preliminary study by the US National Institutes of Health (NIH) published on October 13, people who have received 1 dose of Johnson and Johnson vaccines if they receive a booster dose of 2 with mRNA technology vaccines for antibody levels. superior to injection of the same type.

In a study conducted by the US National Institutes of Health (NIH), researchers organized volunteers into nine groups of about 50 people each.

These people were given one of three vaccines approved for emergency use in the US (Pfizer, Moderna and Johnson & Johnson), followed by a booster shot. There were 3 groups vaccinated with the same type of vaccine, 6 groups were vaccinated with another vaccine.

Researchers found that people who received a Johnson & Johnson (J&J) shot followed by a Moderna booster had a 76-fold increase in antibody levels over 15 days. Meanwhile, those who received J&J booster shots only quadrupled in the same time period.

Similarly, a booster shot of Pfizer-BioNTech raised antibody levels in people with 1 J&J shot 35-fold.

Even so, the team cautions against the small size of the study and that it hasn’t followed the volunteers long enough to determine if they experience rare side effects.

J&J was once considered a “game changer” when the COVID-19 vaccine developed by it only needed a single injection.

There are currently about 15 million people in the US who have been vaccinated with J&J and are anxious to answer the question: is a booster shot needed or not?

According to the US Food and Drug Administration (FDA), the data J&J provided to prove the need for booster injections is “weak”. Preliminary research published on October 13 will certainly heat up the debate around the second dose of the J&J vaccine, according to the report. New York Times.

In addition to J&J, the FDA is also considering a booster shot for people who have received the Moderna vaccine. A group of scientists from the agency said that no injection is needed because the effectiveness of the second dose is still high.

The FDA’s Vaccine Advisory Council will meet on October 14 and 15 to vote on whether to give Moderna, J&J a booster shot. The Vaccine Advisory Committee of the Centers for Disease Control and Prevention (CDC) will also meet next week to vote on the same topic.

If both agencies agree, Americans can receive a booster shot of J&J, Moderna vaccine as early as next week.

On September 21, J&J announced the results of a clinical trial showing that if the second injection is given about eight weeks after the first, the risk of patients having mild to severe symptoms will be reduced by 94%. The effectiveness level of 1 injection is 74%.

Also according to J&J, the amount of antibodies when injecting the 2nd injection within 8 weeks after the 1st dose will increase from 4 to 6 times. Another trial also conducted by J&J showed that if the second injection is given about 6 months after the first dose, the amount of antibodies will increase up to 12 times.

.

Leave a Reply

Your email address will not be published. Required fields are marked *